Detalhe da pesquisa
1.
Discovery of the covalent SARS-CoV-2 Mpro inhibitors from antiviral herbs via integrating target-based high-throughput screening and chemoproteomic approaches.
J Med Virol
; 95(11): e29208, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37947293
2.
Human Carboxylesterase 1A Plays a Predominant Role in Hydrolysis of the Anti-Dyslipidemia Agent Fenofibrate in Humans.
Drug Metab Dispos
; 51(11): 1490-1498, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37550069
3.
A rationally engineered specific near-infrared fluorogenic substrate of human pancreatic lipase for functional imaging and inhibitor screening.
Analyst
; 148(10): 2225-2236, 2023 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37092796
4.
Licochalcone A Derivatives as Selective Dipeptidyl Peptidase 4 Inhibitors with Anti-Inflammatory Effects.
J Nat Prod
; 86(7): 1824-1831, 2023 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37337963
5.
Synthesis and biological evaluation of esculetin derivatives as potential anti-HBV agents.
Med Chem Res
; 32(5): 899-909, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37056462
6.
[Strategy and challenge of innovative drug research and development from clinically effective ingredients of traditional Chinese medicine].
Zhongguo Zhong Yao Za Zhi
; 48(7): 1705-1710, 2023 Apr.
Artigo
em Chinês
| MEDLINE | ID: mdl-37282944
7.
Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb-drug interactions in antiviral therapy.
Acta Pharmacol Sin
; 43(4): 1072-1081, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-34183756
8.
Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment.
Bioorg Med Chem
; 29: 115851, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33218896
9.
Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors.
Bioorg Med Chem
; 29: 115853, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214035
10.
Paeonone A, a novel nonanortriterpenoid from the roots of Paeonia lactiflora.
Bioorg Chem
; 110: 104783, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33714021
11.
[Analysis of peptides and proteins from Asini Corii Colla using nano LC-Q-Exactive-MS/MS].
Zhongguo Zhong Yao Za Zhi
; 46(24): 6422-6434, 2021 Dec.
Artigo
em Chinês
| MEDLINE | ID: mdl-34994135
12.
[Construction and application of pharmacophore model of human carboxylesterase 2 inhibitors].
Zhongguo Zhong Yao Za Zhi
; 46(3): 638-644, 2021 Feb.
Artigo
em Chinês
| MEDLINE | ID: mdl-33645031
13.
Reversible and Irreversible Inhibition of Cytochrome P450 Enzymes by Methylophiopogonanone A.
Drug Metab Dispos
; 49(6): 459-469, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811108
14.
Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of Paeonia lactiflora.
J Nat Prod
; 83(10): 2940-2949, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32951423
15.
Pancreatic Lipase Inhibitory Cyclohexapeptides from the Marine Sponge-Derived Fungus Aspergillus sp. 151304.
J Nat Prod
; 83(7): 2287-2293, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32662266
16.
Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2.
Bioorg Chem
; 105: 104367, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33080495
17.
Inhibition of pancreatic lipase by environmental xenoestrogens.
Ecotoxicol Environ Saf
; 192: 110305, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32070782
18.
[Research progress in application and mechanism of Schisandrae Chinensis Fructus for prevention and treatment of liver diseases].
Zhongguo Zhong Yao Za Zhi
; 45(16): 3759-3769, 2020 Aug.
Artigo
em Chinês
| MEDLINE | ID: mdl-32893568
19.
[Investigation of modulating effect of Qingfei Paidu Decoction on host metabolism and gut microbiome in rats].
Zhongguo Zhong Yao Za Zhi
; 45(15): 3726-3739, 2020 Aug.
Artigo
em Chinês
| MEDLINE | ID: mdl-32893565
20.
Biflavones from Ginkgo biloba as inhibitors of human thrombin.
Bioorg Chem
; 92: 103199, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31446241